ANTI-KETOSIS

Calcium is the main component of bones and teeth. It has chief metabolic functions in the animal bodies and is also essential for muscle activity, skeleton, blood clotting, nerve transmission and dynamics of enzyme function. Calcium metabolism at calving is one of the most important animal health factors influencing the production, reproduction and feed conversion efficiency as it plays a major role in the absorption of nutrients (modification of the cell permeability).

Iron is essential for a wide variety of the metabolic processes of living organisms, due to its chemical transitional property. Iron is present in the different forms of heme and the iron-sulfur (Fe-S) cluster binding protein, which plays an important role in various enzymatic reactions such as aerobic respiration, TCA-cycle function and DNA synthesis as well as oxygen transport and storage. It is a substantial component of red blood cells participating to the blood’s structure and improves the functioning of organs and tissues.

Zinc is an essential nutrient for animals, functioning in enzyme systems and being involved in protein synthesis, carbohydrate metabolism, and many other biochemical reactions. Severe zinc deficiency causes numerous pathological changes, including skin parakeratosis, reduced or cessation of growth, general debility, lethargy, and increased susceptibility to infection.

Magnesium is needed for more than 300 biochemical reactions in the body. It helps to maintain normal nerve and muscle function, supports a healthy immune system, keeps the heartbeat steady, and helps bones remain strong. It also helps adjust blood glucose levels. It aids in the production of energy and protein, improves the digestibility of feed and improves the reproduction.

Manganese is concentrated in the animal bones. It is an important cofactor for many enzymes involved in energy and protein metabolism. Mn is also required for mucopolysaccharide synthesis. This is a major component in the organic matrix of bones. Consequently, deficient animals have normal tendon growth but slow bone growth. This leads to symptoms such as perosis in chicks and crooked calf in other animals.

Phosphorus is very important for all animals for healthy muscles, bones and teeth development, steady digestion, healthy function of the energy metabolism and is an inevitable macro element for reproduction. Deficiency of Phosphor will cause the body to use up phosphor reserve in bone tissues as compensation, however if it isn’t replenished in a short period, issues will arise in all bodily functions and will cause the animals to eat objects with no nutritional value.

Selenium is a component of glutathione peroxidase, an enzyme for the removal of lipid peroxides. Selenium is very important in fertility and helps muscular development. Se is also a component of two other selenoproteins. The midpiece of sperm requires selenoprotein. Microbes in the rumen replace S with Se in their S-containing amino acid synthesis. They are absorbed in the duodenum as amino acids. White muscle disease and exudative diathesis are two Se deficiency symptoms, which can be treated with both vitamin E and Se. Deficient animals also show liver necrosis. Selenium prevents oxidative damage to tissues by offering an antioxidant action and protects against cell damage.

Vitamin A is necessary for support of growth, health and life of major animal species. In the absence of vitamin A, animals will cease to grow and eventually die. Vitamin A and its derivatives, the retinoids, have a profound influence on organ development, cell proliferation, and cell differentiation and their deficiency originates or predisposes animals to a number of disabilities.

Vitamin D the primary function of Vitamin D is to elevate plasma calcium and phosphorus to a level that will support normal mineralization of bone as well as other body functions. It is now realized that Vitamin D is not only important for mineralization and skeletal growth but has many other roles in regulation of the parathyroid gland, in the immune system, in skin, cancer prevention, in metabolism of foreign chemicals and in cellular development and differentiation.

Vitamin E has been shown to be essential for integrity and optimum function of reproductive, muscular, circulatory, nervous, and immune systems. One of the most important functions is its role as an intercellular and intracellular antioxidant. Vitamin E is part of the body’s intracellular defense against the adverse effects of reactive oxygen and free radicals that initiate oxidation of unsaturated phospholipids and critical sulfhydryl groups.